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Investigating mechanisms underlying the impaired hypoxia response in C9Orf72-related MND
Read about research we fund - Investigating how C9orf72 MND potentially causes nerve cells to no longer respond to oxygen deprivation and how this might lead…
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Understanding the role of NEAT1 in energy metabolism in MND
Read about research we fund - Investigating the role of an RNA molecule called NEAT1 plays in MND.
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Death of Rob Burrow CBE
Death of Rob Burrow CBE
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Developing AAV-GRN gene therapy for MND
Find out more about research we fund: Developing AAV-GRN gene therapy for Motor Neuron Disease
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Role of axonal transport in cell models carrying MND mutations
Find out more about research we fund: To establish whether axonal transport deficits in fast motor neurones are a general feature of MND, by comparing…
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MIROCALS: Efficacy and safety of low-dose Interleukin-2
Read about research we fund - Testing whether Interleukin-2 could be a potential treatment for MND.
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Developing a new gene therapy as a tool to rescue TDP-43 related gene changes in MND
TBC
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Home initiation and monitoring of non-invasive ventilation versus hospital-based care in people with MND
Read about research we fund - Investigating whether home-based treatment using non-invasive ventilation could be more widely used for people living with MND.
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Tofersen given green light by the European Commission
Tofersen given green light by the European Commission for treating people with MND
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Investigating individualised effects of low-dose interleukin-2 throughout the MIROCALS Clinical Trial
Read about research we fund - Using RNA from the MIROCALS trial to understand the effect IL-2 antibody treatment has on the immune system.
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