Here you can find more information about the projects we are funding that are developing the treatment pipeline. Click on a project to find out more information and what the project means to a person living with MND.
These projects aim to turn the most promising scientific discoveries into potential new treatments. New treatments that have been proven safe and effective by all other methods are then carefully tested in people.
Development of an SRSF1-targeted gene therapy for C9orf72 MND/FTD
Dr Guillaume Hautbergue
Development of RAR class ligands for treatment of MND
Prof Peter McCaffery
MND Association and LifeArc Joint Collaborative Partnership- United2EndMND - Phase 1
Prof Ammar Al-Chalabi and Prof Chris McDermott
Developing a novel cell therapy approach to restore lost muscle function in MND
Dr Barney Bryson
Developing and testing a new gene therapy approach for TDP-43 associated MND
Prof Pietro Fratta
MIROCALS: Efficacy and safety of low-dose Interleukin-2
Dr Gilbert Bensimon
The role of TBK1-dependant immune signalling pathways in MND
Dr Valeria Gerbino
Analysis of candidate compounds for drug repurposing in MND
Prof Kevin Talbot/Dr Emily Carroll
Assessing the dosing and effectiveness of compounds targeting TDP-43 aggregation in MND
Dr Mark Baker