Our aim is to provide people with MND the opportunity to take part in research studies. Below we list research projects that currently recruit participants for their study. These do not always involve testing a treatment (clinical trials). Most are focused on understanding the causes of MND, and improving diagnosis, care and quality of life of people affected by the disease.

To get notified about new research opportunities by email, you may wish to sign up to our MND Research list and newsletter. You can also find the clinical research projects taking place in the UK on the UK MND Clinical Studies Group website.

Take part in research areas

Treatment Trials

Tofersen

Recruiting people with asymptomatic SOD1-MND in Sheffield

MND SMART (platform trial)

Recruiting people with MND UK-Wide

Triumeq

Recruiting people with MND across the UK

ION363/Jacifusen

Recruiting people with FUS-ALS in London

Dazucorilant

Recruiting people with ALS in Stoke

MAGNET

Recruiting people with MND in London

Symptom Management

Assessment and management of cough and secretion problems in MND

Recruiting healthcare professionals supporting people with MND UK-wide

OptiCALS: A Randomised Controlled Trial to evaluate a nutritional management intervention

Recruiting people with MND and their carers UK-wide

TVLife: Understanding living with tracheostomy ventilation for MND and the implications for quality of life

Recruiting people with MND, family member and healthcare professionals UK-wide

SETTLE: Investigating how to increase cough strength by improving "cough assist" devices

Recruiting people with MND around London

Service users’ and carers’ perspectives on the use of ultrasound in swallowing assessment and management

Recruiting people with MND, family members and carers UK-wide

Biomarker Studies

ALS Biomarker Study: Collecting biological samples to search for biomarkers

Recruiting people with MND, healthy controls and neurological controls in London

C9orf72 Cohort Study: Collecting biological samples to search for causes of C9orf72-MND

Recruiting people with MND, family members and healthy controls in Oxford

Living Lab: Developing new technologies to help people with long-term diseases live at home for longer

Recruiting people with MND and older adults (65+) in London

AMBRoSIA: Searching for unique fingerprints of MND for faster diagnosis

Recruiting people with MND, first-degree relatives and healthy controls UK-wide

MIND MAPS ALS: Using neuroimaging to understand the mechanisms of ALS

Recruiting people with MND in London

Improving Wellbeing

TONiC: Examining the factors influencing qualify of life in neurological conditions

Recruiting people with MND UK-wide

Understanding the impact of a virtual peer support programme on wellbeing and caregiver burden

Recruiting peer supporters and carers UK-wide

Investigating help-seeking behaviour in informal carers of people living with MND

Recruiting informal carers of someone with MND UK-wide.

Online peer support for people living with long-term conditions: A feasibility randomised controlled trial

Recruiting people with long term health conditions UK-wide

Other Studies

MND Register: Collecting information about every person living with MND in England, Wales and Northern Ireland

Recruiting people with MND in England, Wales and Northern Ireland

Developing a stimulation-free remote motor unit number estimate (REMUNE) in MND

Recruiting people with MND, their carers and family members in London

LTC study: Evaluating a new scale designed to measure mood in people living with a long-term physical health condition

Recruiting people with MND

Exploring the behaviour and lifestyles of people with FTD

Recruiting people with FTD/ FTD-MND world-wide

Sheffield MND Research Advisory Group

Recruiting people with MND, their carers and family members

Ear Switch: A new ear-based assistive communication device

Recruiting people who can 'ear rumble' UK-wide

Understanding how people living with MND make decisions about treatment

Recruiting people with MND UK-wide

Investigating the role of exercise in modifying neurodegeneration related to MND

Recruiting people with a C9orf72 gene mutation

Eating and Drinking with Acknowledged Risks: A Comparison of Japan and the UK

Recruiting healthcare professionals UK-wide