Collecting biological samples to search for biomarkers.

The ALS biomarkers study is a research project conceived with the ultimate goal of understanding more about what goes wrong in ALS (the most common form of MND) and how the disease develops from an initial faulty event. The study aims to discover a biomarker to speed up the diagnosis of MND, to monitor its progression and assess whether a new therapy may be effective.

Taking Part

What does taking part involve?

Participants will be asked to donate a sample of biological fluid (blood and urine) every three months. You will also be given the option to donate a sample of cerebrospinal fluid (CSF) – the fluid found in the spinal cord – as well as a skin sample (both of these samples can only be donated for a maximum of three time points).


Who can take part?

  • People living with ALS
  • Healthy controls (people without ALS)
  • Neurological controls (people affected by other neurological disorders)

How can I take part?

Please contact Dr Andrea Malaspina ([email protected]) to show your interest in the study.

Study location

Barts and London MND Care Centre (Royal London Hospital, EH1 1BB)