Are you interested in taking part in research studies? There are plenty of opportunities to get involved in a wide range of different studies. This page highlights research projects which are currently looking for people to take part. These studies include those which are testing a treatment (in clinical trials), as well as studies which are focused on better understanding the biology of MND and improving care and quality of life for people with and affected by MND.

If you would like to receive research participation opportunities straight to your email inbox, sign up to our MND Research List and Research Monthly newsletter. You can also find out about research projects taking place in the UK on the UK MND Clinical Studies Group website.
 

Treatment Trials

These are clinical trials which are testing potential treatments for MND, currently recruiting in the UK. 

MND SMART (platform trial)

Recruiting people with MND UK-Wide

QRL-201

Recruiting people with MND in London

MAGNET

Recruiting people with MND in London and Stoke

EXPERTS-ALS

Recruiting people with MND UK-wide

Symptom Management

These studies are investigating better ways to manage symptoms associated with MND, with the aim of improving quality of life for people living with MND.

SETTLE: Investigating how to increase cough strength by improving "cough assist" devices

Recruiting people with MND around London

OptiCALS: A Randomised Controlled Trial to evaluate a nutritional management intervention

Recruiting people with MND and their carers UK-wide

DENIM trial: Delivering Effective Non-Invasive Ventilation in Motor Neuron Disease

A trial to improve delivery of non-invasive ventilation

Biomarker Studies

These studies may ask you to donate biological samples, such as blood or urine, or take part in clinical tests, such as brain scans, to help find new biomarkers for MND. Biomarkers are markers in the body which can measure changes that are happening in the body. Biomarkers could be helpful for earlier diagnosis of MND, tracking changes in disease over time, or monitoring treatment response.

ALS Biomarker Study: Collecting biological samples to search for biomarkers

Recruiting people with MND, healthy controls and neurological controls in London

ACORN: A C9orf72 National Study

Recruiting people with MND, family members and healthy controls UK wide

Improving Wellbeing

These studies are investigating better and more effective ways to support people living with and affected by MND, to improve quality of life. 

TONiC: Examining the factors influencing qualify of life in neurological conditions

Recruiting people with MND UK-wide

Understanding the impact of a virtual peer support programme on wellbeing and caregiver burden

Recruiting peer supporters and carers UK-wide

iDeliver MND: Improving psychological support in MND

Recruiting people with MND and informal carers

Exploring how changes in behaviour affect quality of life for people living with MND

Recruiting people with MND in the UK

ChiMND: Complex Homecare in MND

Recruiting homecare workers with experience of providing complex homecare to people with MND

Navigating the Unknown: Post-Diagnostic Support Needs of Informal Carers in MND

Recruiting informal (unpaid) carers in the UK

Technology and Tools

These studies are using new technology and tools to improve diagnosis, care, and quality of life for people living with and affected by MND.

MND Register: Collecting information about every person living with MND in England, Wales and Northern Ireland

Recruiting people with MND in England, Wales and Northern Ireland

TiM-R: A remote platform for MND research

Open to people with MND

Measuring caregiver stress using smartphone surveys

Recruiting family caregivers UK-wide

CognoMND™: A digital tool to identify changes in thinking and behaviour

Recruiting people living with MND and carers

Developing a decision aid for genetic testing in MND

Recruiting people with MND and their close relatives

Understanding user experience and satisfaction of cervical neck collars

Recruiting people who use cervical neck collars

Patient and Public Involvement (PPI)

PPI studies are an opportunity to get involved in the design of a project, activity or service. In PPI studies, researchers work with people living with and affected by MND to make sure their research is relevant, beneficial, and important to the MND community.

Sheffield MND Research Advisory Group

Recruiting people with MND, their carers and family members

Improving the data collected by MND registries

Recruiting people with MND and their carers in Lancaster

Involving people with MND in making decisions about their care

Recruiting people living with and affected by MND

Motor Neurone Disease Research Data Catalyst

Recruiting people with MND, carers and family members

Other Studies

These studies do not fit into any of the other categories on this page, and may include studies for healthcare professionals, improving clinical practice etc. 

Exploring the experiences of healthcare professionals who work with people with MND

Recruiting healthcare professionals in the UK

The use of reproductive medicine options in families with inherited MND

Recruiting people with or affected by inherited MND in the UK

Exploring Variation in Social Care Needs Assessments

Recruiting people living with MND and unpaid carers