There are many clinical trials investigating various treatments for MND across the world. Here we focus on trials that are in the spotlight and provide you with updates on the latest results and related news.

Unsure of some of the wording used in these clinical trials pages? Our glossary gives easy to understand definitions of commonly used words when discussing clinical trials. You can access the clinical trial glossary.

Are you interested in taking part in a clinical trial? Use our new tool which lets you look for trials near you or look for trials which say they are "open" below. Head to our take part in research to see more research opportunities.

United Kingdom Trials

AMX0035 (PHOENIX)

Status: Awaiting results

Tofersen (ATLAS)

Recruiting status: open (people with asymptomatic SOD1-MND)

Dazucorilant (DAZALS)

Recruiting status: Open

ILB

Status: Awaiting results

ION363/Jacifusen

Recruiting status: Open (for people living with FUS-ALS)

MAGNET Platform Trial

Recruiting status: Open

MND SMART

Recruiting status: Open

QRL-201 (ANQUR)

Recruiting status: In preparation

Taurourdeoxycholic acid (TUDCA-ALS)

Status: Awaiting results

Triumeq (LIGHTHOUSE 2)

Recruiting status: Open

International Trials

CuATSM

Awaiting topline results

HEALEY Platform Trial

Recruiting status: Open

Ibudilast/MN-166

Recruiting status: Open

Masitinib

Recruiting status: Open

Metformin

Recruiting status: Open

Trimetazidine (MetFlex)

Awaiting topline results

Completed Trials

Arimoclomol

Completed 2021

CNM-Au8 (RESCUE-ALS)

Closed 2021

Edaravone/Radicava

Completed 2023

Interleukin-2

Completed 2022

Levosimendan (ODM-109)

Completed 2020

Memantine

Completed 2022

NP001

Completed 2015

NurOwn

Closed 2021

Nuedexta

Closed 2016

Oral Edaravone (FNP122)

Closed 2023

Pegcetacoplan/APL-2

Closed 2023

Ravulizumad/Ultomiris

Closed 2021

Reldesemtiv/Tirasemtiv

Closed 2023

RT001

Closed 2022

SAR443820 (HIMALAYA)

Closed 2023

Tegoprubart (AT-1501)

Closed 2022

WVE-004 (FOCUS-C9)

Closed 2023

Due to the sheer number of clinical trials investigating treatments for MND taking place at the moment, we have not included every trial. Please use the button below to find out about more MND trials currently recruiting around the world.

Currently recruiting worldwide

This link will take you to clinicaltrials.gov, the largest clinical trials database.

 

Last updated: 20/02/2024