Resources for researchers

We are keen to support the activities of MND researchers. Here you can find how we can help with your research, from sourcing samples, helping with participant recruitment, to providing grants for open access publishing. You can also find a list of external resources you may find useful.

External resources

ALS Online Database (ALSoD)

The ALS Online Database (ALSoD) is a freely available database that has been transformed from a single gene storage facility recording mutations in the SOD1 gene, to a multigene ALS bioinformatics repository and analytical instrument which combines genotype, phenotype, and geographical information with associated analysis tools, allowing you to understand gene variants you find.

ALSoD Text

ALS Reproducible Antibody Platform (ALS RAP)

ALS-RAP was formed to ensure the availability of the highest quality, validated antibodies developed using standard operating procedures that will be openly shared with the ALS research community. Notably, no form of intellectual property protection or patents will be filed for all new reproducible antibodies fully discovered and developed by ALS-RAP. This collaborative effort, based on open science and complete freedom to operate, will ensure the use of the highest-quality tools to increase the success of future drug discovery.

Als Rap

ALS Research Forum

An online resource for ALS/MND researchers managed by Prize4Life, The ALS Association and in collaboration with Alzforum. It has details of the latest ALS/MND research and drug development news, a database of drugs in development for ALS, and other resources for researchers.

Alzforum

The Alzforum is a dynamic web-based scientific community dedicated to understanding Alzheimer's disease and other related neurodegenerative disorders. The website reports on the latest scientific findings, creates and maintains public databases of research data as well as producing online discussion forums.

Alzforum

Dementia Research Funding portal

The Dementia Research Funding Portal provides researchers with the latest funding opportunities in dementia research. This includes up to date research funding calls and deadlines, other useful resources and events.

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Guidelines on the use of pre-clinical models in MND research

For many years, translation of apparent therapeutic successes from in vivo models of ALS to the human disease has proven difficult. In 2005 a group of European MND researchers began work on some guiding principles of preclinical research and therapy development. A consensus paper was published in 2010: Ludolph et al ALS 2010;11(1-2):38-45.

PRO-ACT Database

PRO-ACT (Pooled Resource Open-Access ALS Clinical Trials Database) is a pooled resource of ALS clinical trial data, created by merging data from existing public and private clinical trials. Launched in December 2012, it contains 10,700 unique patient records from the treatment and placebo arms of 23 phase II and phase III ALS/MND trials.

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ReCCoB blog

This blog is an independent one-stop-shop for all the latest news and views from amyotrophic lateral sclerosis/motor neurone disease conferences and workshops from around the world, written by professionals for professionals. It aims to whet the appetite of future delegates with snippets of information about these events and what it is like to attend. This blog will never take away the value of attending but will give a sense of excitement and added value to those who do, or who would consider attending in the future.

If you’re attending an ALS/MND conference and want to contribute to the blog, please contact us at research@mndassociation.org.

SPiQE: Surface Potential Quantification Engine

SPiQE is the brainchild of a collaboration between neurologists at King’s College London and bioengineers at Imperial College London. It combines the very latest in surface electrode technology with sophisticated spike-detection software.

SPiQE functions as an automated analytical pipeline for the detection of spontaneous and voluntary muscle activity. It is non-invasive and well-tolerated by patients. Importantly, this means muscle recordings can be longer than ever before and can be repeated at regular time intervals.

UK Brain Banks Network

The Medical Research Council (MRC) led the initiative to develop the UK Brain Banks Network. This network will provide high quality brain tissue to scientists and clinicians in order for them to carry out cutting edge neuroscience research. For further information please see their website.

Veterans Affairs Biorepository Brain Bank

The US Veterans Affairs Biorepository Brain Bank (VABBB) was established in 2006 to promote and support research into ALS and other illnesses that affect veterans by collecting brain and spinal cord tissues, along with relevant clinical data, essential for such research. ALS researchers are invited to apply for tissue and data collected from veterans with ALS. For more information please see their website.

Can't find what you're looking for?

If you can't find what you're looking for, please contact us as we may know someone who can help.

We're keen to make this page a useful place of reference. If you'd like to share a resource with others, please contact us to add it.

 

For further information and support contact our MND Connect helpline

mndconnect 0808 802 6262