TONiC: quality of life in neurological conditions

Examining the factors influencing quality of life in neurological conditions

TONiC (Trajectories of Outcome in Neurological Conditions) is the largest study in the UK examining the factors that influence quality of life in patients with neurological conditions, including MND. TONiC aims to have a significant and positive impact on the lives of all patients living with neurological conditions, regardless of symptoms, stage of illness, age or social status.

What does taking part involve?

If you are a person with MND, you will be asked to complete paper-based questionnaires, which can be filled out at home at your leisure. The questionnaires will ask you about different aspects of your quality of life, from symptoms you experience, to worries you have and how your condition impacts on your home environment.

Study locations

Swansea, Basildon and Thurrock, Brighton and Sussex, Cambridge, Cardiff & Vale, Cheshire and Wirral, Cumbria, Dartford & Gravesham, Edinburgh, Devon & Exeter, Carmarthenshire, Kings Lynn, Lincolnshire, London - King's College, London - Royal Free, London - North West, London - North East, Leicester, Maidstone and Tunbridge Wells, Newcastle, Northern Devon, Norfolk & Norwich, Oxford, Peterborough, Plymouth, Portsmouth, Preston, Salford, Sheffield Southampton, University College London, Suffolk, Staffordshire and Stoke, Worcestershire, York and Scarborough, Liverpool

Who can take part?

• People living with MND

How can I take part?

People with MND who wish to take part should contact their chosen participating centre, details of which can be found on the TONiC website, or you can contact the study team direct (0151 529 5668/2980) or e-mail


This study is funded by the MND Association, Biogen, Novartis, MERCK, Roche, TEVA, NHS, Genzyme: A Sanofi Company, and The Walton Centre NHS Foundation Trust .

Expiry date: N/A

For further information and support contact our MND Connect helpline

mndconnect 0808 802 6262