Introduction to the UK MND Collections

The UK MND Collections (formerly known as the UK MND DNA Bank) is a resource, combining more than 3,000 blood samples and accompanying clinical information; as well as epidemiology data from 400 participants, including people with MND, controls and family members.

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The DNA Bank was the original Collection of over 3,000 blood samples, which are stored at CIGMR (Centre for Integrated Genomic Medical Research) in Manchester, UK. The DNA Bank also has clinical information (divided into a minimum and extended dataset) which is available to researchers.

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The Cell Lines Collection offers a sub set of the DNA Bank samples as lymphoblastoid cell lines and peripheral blood lymphocytes. This was originally set up as a back-up for the DNA Bank samples running out. However, these cell lines have proven to be an excellent resource in their own right and also enable the creation of induced Pluripotent Stem Cells (iPSCs).

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The Epidemiology Collection has just over 200 patient and matched control surveys that include extensive environmental and lifestyle data (both from self-report questionnaires and telephone interviews) as well as a subset of genomic DNA samples.

Combining all three collections produces a very rich dataset for researchers to use to study MND. A heartfelt thank you to all participants, without whom this invaluable resource would not exist.

How to apply for samples or data

Please note that the minimum dataset is provided for all samples, but the extended dataset needs to be requested at the time of applying for access to the samples. If you have any questions, please email mndcollections@mndassociation.org.

For further information and support contact our MND Connect helpline

mndconnect 0808 802 6262